The Covonix Lumivir™ multimodal solution combines low light level luminometry on saliva samples in combination with method 1, method 2, method 3 and method 4. The first generation test is designed to aid in the diagnosis and management of an infection. The second generation test will leverage COVID-19 specific capture and detection antibodies to enable diret antigen detection at the point of care. Data is collected locally by the instrument and transferred by Bluetooth LE to a mobile app where the data is encrypted and uploaded to a cloud based server for report generation and combination with EHR and contact tracing. The reports can then be sent to telehealth physicians for interpretation and then provided to nurses and other field clinicians to assist in the identification and management of COVID-19, for instance making ‘Return-to-Work’ and ‘Return-to-School’ decisions.
When a swab or saliva sample of a patient is exposed to chemical reagents, light is produced indicating an abnormally elevated level of a key protein, indicative of an infection. In a second geneartion, COVID-19 specific antibodies are used to capture minute quantities of virus while detection antibodies are conjugated with reporter enzymes so that light can be used as a readout for the presence of the virus. Because luminometers leverage low light level pn and PIN photodiodes, the delicate photo-currents can be converted into measureable signals which can be integrated, quantified, transferred and analyzed by the local app and cloud based report analytics.
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